Association between plasma gamma-glutamyltransferase fractions and metabolic syndrome among hypertensive patients

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Increased serum gamma-glutamyltransferase activity in patients with metabolic syndrome.

OBJECTIVES Accumulating data indicate that serum gamma-glutamyltransferase (GGT) activity represents a true marker of atherosclerotic cardiovascular disease and has prognostic importance. In this study, we sought to evaluate serum GGT activity in patients with metabolic syndrome (MetS). STUDY DESIGN We enrolled 232 patients (mean age 60.4 years) from our outpatient cardiology clinic, 117 with...

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Circulating gamma-glutamyltransferase fractions in cirrhosis.

BACKGROUND & AIMS Four gamma-gultamyltransferases (GGT) fractions (b-, m-, s-, and f-GGT) have been identified in human plasma and their concentrations and ratios vary in different pathological conditions. To assess the behaviour of fractional GGT in cirrhotic patients evaluated for liver transplantation. METHODS This was a single-centre, cross-sectional study; GGT fractions were determined b...

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The Association Between Metabolic Syndrome and Serum Leptin

Objectives: The relation of metabolic syndrome components, insulin resistance and leptin has been studied in elderly women. Methods & Materials: In this cross sectional study, among 225 subjects≥60 year old who were residents of Kahrizak Charity Foundation, 133 (56 men & 77 women) were selected by cluster random sampling. Fasting serum TG, Total Cholesterol, HDL, and leptin levels were measu...

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Association between serum gamma-glutamyltransferase level and prehypertension among US adults.

BACKGROUND Higher serum gamma-glutamyltransferase (GGT) levels, a marker of oxidative stress, are implicated in the development and progression of hypertension; however, data from non-Caucasian ethnicities are limited. Also, currently there is little data available on the association between serum GGT level and clinically relevant blood pressure (BP) categories earlier in the disease continuum,...

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Gamma-Glutamyltransferase Fractions in Human Plasma and Bile: Characteristic and Biogenesis

Total plasma gamma-glutamyltransferase (GGT) activity is a sensitive, non-specific marker of liver dysfunction. Four GGT fractions (b-, m-, s-, f-GGT) were described in plasma and their differential specificity in the diagnosis of liver diseases was suggested. Nevertheless fractional GGT properties have not been investigated yet. The aim of this study was to characterize the molecular nature of...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2017

ISSN: 2045-2322

DOI: 10.1038/s41598-017-12356-w